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Doxycycline is a broad-spectrum antibacterial synthetically derived from oxytetracycline. Doxycycline capsules USP, 75 mg, and mg contain Doxycycline monohydrate equivalent to 75 mg, and mg of Doxycycline for oral administration. Doxycycline oral tablet is a prescription drug that’s available as the brand-name drugs Acticlate, Doryx, and Doryx MPC. It’s also available as a generic drug. Doxycycline is a prescription antibiotic medication indicated for the treatment of certain infections and diseases. Learn about side effects, drug interactions, dosages, warnings, and more. 10%; Dosage Considerations – Should be Given as Follows: General Dosage. Initial: mg/day divided twice daily orally/intravenously (IV) on first.


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This information is intended for use by health professionals. Since Doxycycline is a member of the tetracycline group of antibiotics, it may be expected to be useful in the treatment of infections, which respond to other tetracyclines, such as: Absorption is rapid effective concentrations are attained as from the first hourand the peak serum concentration occurs after 2 to 4 hours. This may be fatal. 10 mg doxycycline Описание препарата ДОКСИЦИКЛИН (DOXYCYCLINE). создано в году на основании инструкции, размещенной на официальном сайте Минздрава РФ. Форма выпуска, упаковка и состав. Клинико-фармакологич. группа. Фармако-терапевтическая группа. Фармакологическое действие. Фармакокинетика. DOXYLAN (DOXYCYCLIN) TBL MG N10 Инструкция.Цена € в Риге,Латвии.Оптимальный поиск аналогов лекарств.Скидки. Лучшая цена и где купить DOXYLAN (DOXYCYCLIN) TBL MG N ✔ Купить ДОКСИЦИКЛИН МГ КАПСУЛЫ №10 в интернет аптеке в Москве. ✔ Цена - ⭐31,40 руб.руб.⭐ ✔ Есть в наличии. ✔ Инструкция по применению ДОКСИЦИКЛИН МГ КАПСУЛЫ №10 описание, отзывы, состав, аналоги дешевле. ✔ Бесплатная доставка по Москве.  Производители. Барнаульский завод медицинских препаратов (Россия), Белмедпрепараты (Беларусь), Борисовский завод медицинских.

Doxycycline belongs to a class of drugs called tetracyclines. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. This drug works by blocking a bacterial protein from being made. It does this by binding to certain units of the protein. This stops the protein from growing and treats your infection. Doxycycline oral tablet can interact with other medications, vitamins, or herbs you may be taking.

An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully.

Do not use these drugs with doxycycline. Doing so can cause dangerous effects in your body. Examples of these drugs include:. When you take doxycycline with certain drugs, doxycycline may not work as well to treat your condition. This is because the amount of doxycycline in your body may be decreased. Examples of drugs that can cause this type of interaction include:. Taking doxycycline with certain medications raises your risk of side effects from these drugs. An example of a drug that could cause this type of interaction is:.

However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call or go to the nearest emergency room. Taking it again could be fatal cause death.

This means it may not work as well to treat your condition. Some foods that are high in calcium include milk and cheese. If you eat or drink these items, do so at least one hour before taking this drug or one hour after taking this drug. For women of childbearing age who are overweight: You have a higher risk of high blood pressure inside of your skull from this drug. Ask your doctor if this drug is right for you.

For people with a history of intracranial hypertension: There are no adequate studies on the use of doxycycline in pregnant women.

Ask your doctor to tell you about the specific risk to the pregnancy. Call your doctor right away if you become pregnant while taking this drug. For women who are breastfeeding: Doxycycline passes into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication. The kidneys of older adults may not work as well as they used to.

This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. This drug may cause tooth discoloration at the time teeth are developing. This drug should not be used in children who are 8 years of age or younger unless the potential benefit outweighs the risk.

In these children, its use is recommended for the treatment of severe or life-threatening conditions such as anthrax or Rocky Mountain spotted fever, and when no other treatments are available or have been shown to work.

This dosage information is for doxycycline oral tablet. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:. The dosage information below is for the conditions that this drug is most often prescribed to treat. This list may not contain all conditions that your doctor can prescribe this drug for.

If you have questions about your prescription, talk with your doctor. It has not been confirmed that this drug is safe and effective for use in people who are younger than 8 years.

Your doctor may start you on a lowered dosage or a different schedule. This can help keep levels of this drug from building up too much in your body. It has not been confirmed that this drug is safe and effective for use in children younger than 8 years.

Doxycycline oral tablet is used for short-term treatment. Your infection will likely not go away. This may be fatal. Your medication may not work as well or may stop working completely.

You may feel better before you finish your course of treatment, but you should keep taking your medication as directed. Skipping doses or failing to complete the full course of treatment may reduce how well your treatment works. It may also cause antibiotic resistance. If you take too much: You could have dangerous levels of the drug in your body and experience more side effects.

If your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: Other Bacteria Nocardiae and other Actinomyces species Borrelia recurrentis Chlamydophila psittaci Chlamydia trachomatis Mycoplasma pneumoniae Rickettsiae Treponema pallidum Treponema pallidum subspecies pertenue Ureaplasma urealyticum.

Parasites Balantidium coli Entamoeba species. These reports should aid the physician in selecting the most effective antimicrobial. Quantitative methods are used to determine antimicrobial minimum inhibitory concentrations MICs. These MICs provide estimates of the susceptibility of bacteria to antimicrobial compounds.

Quantitative methods that require measurement of zone diameters can also provide reproducible estimates of the susceptibility of bacteria to antimicrobial compounds. The zone size should be determined using a standardized test method. The disk diffusion interpretive criteria are provided in Table 1. For anaerobic bacteria, the susceptibility to Doxycycline can be determined by a standardized test method.

A report of Susceptible S indicates that the antimicrobial is likely to inhibit growth of the microorganism if the antimicrobial drug reaches the concentration usually achievable at the site of infection. A report of Intermediate I indicates that the result should be considered equivocal, and, if the microorganism is not fully susceptible to alternative, clinically feasible drugs, the test should be repeated.

This category implies possible clinical applicability in body sites where the drug product is physiologically concentrated or in situations where high dosage of drug can be used. This category also provides a buffer zone that prevents small uncontrolled technical factors from causing major discrepancies in interpretation.

A report of Resistant R indicates that the antimicrobial drug is not likely to inhibit growth of the microorganism if the antimicrobial drug reaches the concentrations usually achievable at the infection site; other therapy should be selected. Standardized susceptibility test procedures require the use of laboratory controls to monitor and ensure the accuracy and precision of the supplies and reagents used in the assay, and the techniques of the individuals performing the test.

For the diffusion technique using the 30 mcg Doxycycline disk or 30 mcg tetracycline disk, the criteria noted in Table 2 should be achieved. To reduce the development of drug-resistant bacteria and maintain effectiveness of Doxycycline capsules, USP and other antibacterial drugs, Doxycycline capsules, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Doxycycline is indicated for the treatment of the following infections: Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae. Respiratory tract infections caused by Mycoplasma pneumoniae.

Lymphogranuloma venereum caused by Chlamydia trachomatis. Psittacosis ornithosis caused by Chlamydophila psittaci. Trachoma caused by Chlamydia trachomatis , although the infectious agent is not always eliminated as judged by immunofluorescence. Inclusion conjunctivitis caused by Chlamydia trachomatis.

Nongonococcal urethritis caused by Ureaplasma urealyticum. Relapsing fever due to Borrelia recurrentis. Doxycycline is also indicated for the treatment of infections caused by the following gram-negative microorganisms: Chancroid caused by Haemophilus ducreyi.

Plague due to Yersinia pestis. Tularemia due to Francisella tularensis. Cholera caused by Vibrio cholerae. Campylobacter fetus infections caused by Campylobacter fetus.

Brucellosis due to Brucella species in conjunction with streptomycin. Bartonellosis due to Bartonella bacilliformis. Because many strains of the following groups of microorganisms have been shown to be resistant to Doxycycline, culture and susceptibility testing are recommended. Doxycycline is indicated for treatment of infections caused by the following gram-negative microorganisms, when bacteriologic testing indicates appropriate susceptibility to the drug: Respiratory tract and urinary tract infections caused by Klebsiella species.

Doxycycline is indicated for treatment of infections caused by the following gram-positive microorganisms when bacteriologic testing indicates appropriate susceptibility to the drug: Upper respiratory infections caused by Streptococcus pneumoniae.

Anthrax due to Bacillus anthracis , including inhalational anthrax post-exposure: When penicillin is contraindicated, Doxycycline is an alternative drug in the treatment of the following infections: Uncomplicated gonorrhea caused by Neisseria gonorrhoeae. Syphilis caused by Treponema pallidum.

Yaws caused by Treponema pallidum subspecies pertenue. Listeriosis due to Listeria monocytogenes. Actinomycosis caused by Actinomyces israelii. Infections caused by Clostridium species. This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines. The use of drugs of the tetracycline class, including Doxycycline, during tooth development last half of pregnancy, infancy and childhood to the age of 8 years may cause permanent discoloration of the teeth yellow-gray-brown.

This adverse reaction is more common during long-term use of the drugs, but it has been observed following repeated short-term courses. Enamel hypoplasia has also been reported. Use of Doxycycline in pediatric patients 8 years of age or less only when the potential benefits are expected to outweigh the risks in severe or life-threatening conditions e.

Clostridium difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, including Doxycycline capsules, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C.

Hypertoxin producing strains of C. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. Intracranial hypertension IH, pseudotumor cerebri has been associated with the use of tetracyclines including Doxycycline capsules.

Clinical manifestations of IH include headache, blurred vision, diplopia, and vision loss; papilledema can be found on fundoscopy. Women of childbearing age who are overweight or have a history of IH are at greater risk for developing tetracycline associated IH. Concomitant use of isotretinoin and Doxycycline capsules should be avoided because isotretinoin is also known to cause pseudotumor cerebri.

Although IH typically resolves after discontinuation of treatment, the possibility for permanent visual loss exists. If visual disturbance occurs during treatment, prompt ophthalmologic evaluation is warranted.

Since intracranial pressure can remain elevated for weeks after drug cessation patients should be monitored until they stabilize. All tetracyclines form a stable calcium complex in any bone-forming tissue. This reaction was shown to be reversible when the drug was discontinued. Results of animal studies indicate that tetracyclines cross the placenta, are found in fetal tissues, and can have toxic effects on the developing fetus often related to retardation of skeletal development.

Evidence of embryo toxicity has been noted in animals treated early in pregnancy. If any tetracycline is used during pregnancy or if the patient becomes pregnant while taking these drugs, the patient should be apprised of the potential hazard to the fetus. The antianabolic action of the tetracyclines may cause an increase in BUN.

Studies to date indicate that this does not occur with the use of Doxycycline in patients with impaired renal function. Photosensitivity manifested by an exaggerated sunburn reaction has been observed in some individuals taking tetracyclines. Patients apt to be exposed to direct sunlight or ultraviolet light should be advised that this reaction can occur with tetracycline drugs, and treatment should be discontinued at the first evidence of skin erythema.

As with other antibacterial preparations, use of this drug may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, Doxycycline capsules should be discontinued and appropriate therapy instituted.

Incision and drainage or other surgical procedures should be performed in conjunction with antibacterial therapy when indicated. Prescribing Doxycycline capsules in the absence of proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria. Sunscreen or sunblock should be considered. However, the absorption of Doxycycline is not markedly influenced by simultaneous ingestion of food or milk.

Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools with or without stomach cramps and fever even as late as two or more months after having taken the last dose of the antibiotic. If this occurs, patients should contact their physician as soon as possible.

Patients should be counseled that antibacterial drugs including Doxycycline capsules should only be used to treat bacterial infections. They do not treat viral infections e. When Doxycycline capsules are prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed.

Skipping doses or not completing the full course of therapy may 1 decrease the effectiveness of the immediate treatment and 2 increase the likelihood that bacteria will develop resistance and will not be treatable by Doxycycline capsules or other antibacterial drugs in the future. In venereal disease when coexistent syphilis is suspected, a dark-field examination should be done before treatment is started and the blood serology repeated monthly for at least four months.

In long-term therapy, periodic laboratory evaluations of organ systems, including hematopoietic, renal, and hepatic studies should be performed. Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage.

Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracyclines in conjunction with penicillin. Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations.

This can cause your body to process drugs more slowly. Inclusion conjunctivitis caused by Chlamydia trachomatis. You may need to decide whether to stop breastfeeding or stop taking this medication. 10 mg doxycycline
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