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Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's. Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation , where it may significantly increase the time from penetration to ejaculation.

The common, adverse drug reactions side effects are the same as with other PDE 5 inhibitors. The frequent vardenafil-specific side-effect is nausea ; the infrequent side effects are abdominal pain, back pain, photosensitivity , abnormal vision, eye pain, facial edema , hypotension , palpitation, tachycardia , arthralgia , myalgia , rash, itch, and priapism.

One possibly serious, but rare, side effect with vardenafil is heart attack. Also, in rare cases, vardenafil use may cause priapism, a very painful emergency condition that can cause impotence if left untreated. On 18 October , the U. Food and Drug Administration FDA announced that a warning about possible deafness sudden hearing loss would be added to the drug labels of vardenafil, and other PDE 5 inhibitors.

Vardenafil, as with all PDE 5 inhibitors, should not be used by people taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension low blood pressure.

Further, vardenafil causes lengthening of the QT interval. Therefore, it should not be taken by people taking other medications that affect the QT interval such as amiodarone. It is available in 2. Vardenafil should be taken 1 to 2 hours prior to sexual activity , with a maximum dose frequency of once per day.

In some territories, such as the UK, only certain doses may be available. Vardenafil is also available under the name Staxyn as a tablet which dissolves on the tongue rather than being swallowed in the form of a pill.

The USFDA has found vardenafil and other synthetic PDE 5 inhibitors in numerous products marketed as "herbal" supplements or "all natural" products for male enhancement. From Wikipedia, the free encyclopedia. B No risk in non-human studies. S4 Prescription only UK: Archived from the original on Haben Sie bestimmte Fragen zu einem Projekt?

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